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目的探讨心肌血流储备分数(FFR)处于临界值(0.75~0.80)时应用不同的治疗策略对生活质量的影响。方法对60例冠状动脉造影显示冠状动脉病变(狭窄70%~75%)并且FFR处于临界值的冠心病患者随机分为经皮冠状动脉介入治疗组(PCI组,n=30)和药物治疗组(保守组,n=30)进行治疗,平均随访6个月,观察两组主要不良心血管事件(MACE)和西雅图心绞痛量表(SAQ)情况。结果 PCI组和保守组对MACE和SAQ的影响差异无统计学意义(P>0.05)。结论狭窄程度达70%~75%的冠状动脉病变若FFR处于临界值(0.75~0.80),仍可安全地给予药物保守治疗。
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更新时间：2015-05-25
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心肌血流储备分数在冠状动脉临界病变患者中的应用
Application of myocardial fractional flow reserve in patients with borderline coronary artery disease
微创医学 201306期 页码：678-680
作者机构： 广西中医药大学第一附属医院心血管内科
基金信息： 收稿日期: 2013-08-29
- 中文简介
- 英文简介
- 参考文献
Objective To evaluate the effect of different treatment strategies on life quality in patients with myocardial fractional flow reserve ( FFＲmyo) at critical point ( 0． 75 － 0． 80) ． Methods Sixty coronary artery disease ( CAD) patients with 70 － 75% coronary artery stenosis on angiography and FFＲmyo at critical point ( 0． 75 － 0． 80) were randomized into two groups: 30 patients underwent coronary artery stenting ( PCI group) ，and 30 patients received pure drug therapy． Patients were followed up to 6 months． Major adverse cardiac events ( MACE ) and Seattle angina questionaire ( SAQ ) were primary endpoints．Ｒesults Differences in MACE incidence and SAQ scores between two groups were not significant ( P ＞ 0． 05) ． Conclusion Pure drug therapy can be used in patients with lesion of 70% － 75% stenosis and FFＲmyo at critical point ( 0． 75 － 0． 80) ．
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