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目的探讨经口内镜下肌切开术(POEM)治疗贲门失弛缓症(AC)的近期疗效和安全性。方法回顾性分析在该院确诊为AC并接受POEM治疗的10例患者的临床资料,观察记录患者手术情况、治疗效果以及并发症发生情况。结果全组患者均顺利完成POEM术,手术时间120~240 min,黏膜下隧道长度8~12 cm,肌切开长度6~10 cm。术后随访时间2~5个月。10名患者吞咽困难明显改善,未出现手术相关严重并发症。2例术后出现少许出血,1例术后并发肺炎均经内科保守治疗后好转出院;1例于术后3月复查胃镜提示反流性食管炎。结论 POEM可以迅速解除AC患者吞咽困难,短期疗效肯定,但其长期疗效及远期并发症仍有待随访和观察。
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更新时间：2015-05-22
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经口内镜下肌切开术治疗贲门失弛缓症的近期疗效观察
Observation on short-term efficacy of peroral endoscopic myotomy in the treatment of esophageal achalasia
微创医学 201305期 页码：543-546
作者机构： 广西医科大学第一附属医院消化内科
基金信息： 收稿日期: 2013-07-05
基金项目：国家自然科学基金(合同号:8120083;31360221)
- 中文简介
- 英文简介
- 参考文献
Objective To evaluate the efficacy and the safety of peroral endoscopic myotomy( POEM) for esophageal achalasia( AC) ． Methods The clinical data of 10 patients with AC underwent POEM in the First affiliated hospital of Guangxi Medical University were reviewed retrospectively． Surgery circumstance， treatment effect ，and postoperative complication were analyzed． Ｒesults All 10 patients underwent operation smoothly． The operative time was 120 ～ 240 min，the submucosal tunneling length was 8 ～ 12 cm，and the length of endoscopic myotomy of inner circular muscle was 6 ～ 10 cm． The median follow-up period was 3 ( range 2 － 5) months． Dysphagia symptom was improved significantly during the follow-up period in all of them． No serious complications related to POEM was recorded． Two mild bleeding and 1 postoperative pneumonia were cured by internal medicine． One reflux esophagitis was detected by gastroscope 3 months after operation． Conclusions POEM appears to have definite short-term outcomes and can rapidly alleviate dysphagia symptomFurther observations and long follow-up are needed to evaluate long-term outcomes and complications．
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