ObjectiveTo investigate the repair effect of modified autologous platelet-rich fibrin (A-PRF) combined with recombinant human-like collagen mask on female facial skin photoaging. MethodsA total of 80 patients with facial skin photoaging were divided into a control group and a treatment group by drawing lots, with 40 cases in each group. Patients in the control group were treated with recombinant human-like collagen mask (Collgene) for external application, on the basis of which those in the treatment group were additionally treated with A-PRF. Both groups were treated for 1 week. The skin pH value, moisture, elasticity, and grease secretion, as well as skin pigmented spots, wrinkles, texture, and pores were compared between the two groups before treatment, 1 week and 1 month after treatment. And the occurrence of adverse reactions from 1 week to 1 month after treatment was observed. ResultsThe facial skin status improved to various degrees in both groups at 1 week and 1 month after treatment, with the improvement in wrinkles, texture, pores, moisture, elasticity, and grease significantly better in the treatment group than in the control group, as indicated by a significant increase in delicacy and gloss, a decrease in fine wrinkles, and subjective sensation of skin moisturization with fullness and elasticity, etc. No adverse reactions occurred in either group during the observation period. ConclusionUsing A-PRF combined with recombinant human-like collagen mask to repair female facial skin photoaging can improve the moisture and elasticity of facial skin, while reducing grease and fine wrinkles. It has an obvious repair effect on female facial skin photoaging and is worthy of clinical promotion and application.

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