微创医学

目的观察参灵扶正胶囊治疗气虚型HIV感染者的临床疗效。方法采用参灵扶正胶囊治疗气虚型HIV感染者380例,疗程1年,观察指标有临床症状、体征总积分、卡洛夫斯基积分,以及CD4+细胞计数及生存质量的变化情况。结果治疗后感染者症状、体征总积分、卡洛夫斯基积分及CD4+稳定率分别为94.74%、83.95%、96.6%,临床症状、体征总积分和卡洛夫斯基积分,CD4+细胞计数,生存质量中生理领域、心理领域、社会关系及总积分改善显著(P<0.05或P<0.01)。结论参灵扶正胶囊可显著改善气虚型HIV感染者的临床症状和体征,提高感染者的生存质量,对部分感染者的免疫功能有提高或稳定作用。

Objective To investigate the clinical efficacy of Shen Ling Fuzheng Capsule in the treatment of HIV infected patients of Qi deficiency． Method 380 cases of HIV infected patients of Qi deficiency were treated with Shen Ling Fuzheng Capsule for a course of 1 year． The observation index included score of clinical symptoms and signs，Karnovski score，CD4 cell count，and quality of life( QOL) before and after treatment．Ｒesults The HIV-infected persons’ stability rate of score of clinical symptoms and signs，Karnovski，CD4 cell count were 94． 74%，83． 95%，and 96． 6% after treatment ，respectively． Score of clinical symptoms and signs，Karnovski score，CD4 cell count，and QOL improved significantly after treatment( P ＜ 0． 05 or P ＜ 0． 01) ． Conclusion Shen Ling Fuzheng Capsule can significantly improve clinical symptoms and signs and the quality of life of those HIV-infected persons，and can improve or stabilize immunization function in part of the HIV infected patients．

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