目的探讨超声引导下经皮微波消融术治疗肝血管瘤的临床疗效及安全性。方法选择80例肝血管瘤患者为研究对象,采用随机数字表法将其分为对照组和观察组,每组40例。对照组患者接受开腹切除术治疗,观察组患者接受超声引导下经皮微波消融术治疗。比较两组患者的治疗效果、肝功能指标及并发症发生情况。结果两组治疗效果比较,差异无统计学意义(P>0.05)。术前,两组总胆红素(TBil)、丙氨酸转氨酶(ALT)及天门冬氨酸氨基转移酶(AST)水平差异均无统计学意义(均P>0.05);术后,两组TBil、ALT及AST水平均低于术前,且观察组低于对照组(均P<0.05)。观察组并发症发生率为5.00%,低于对照组的22.50%(P<0.05)。结论在肝血管瘤的治疗中,超声引导下经皮微波消融术能获得与开腹切除术相当的治疗效果,且更有利于改善患者的肝功能,降低并发症发生率,值得临床广泛应用。
ObjectiveTo investigate the clinical efficacy and safety of ultrasound-guided percutaneous microwave ablation in the treatment of hepatic hemangioma. MethodsA total of 80 patients with hepatic hemangioma were selected as research objects, and they were divided into control group and observation group by the random number table method, with 40 cases in each group. Patients in the control group were treated by open laparotomy, while patients in the observation group were treated by ultrasound-guided percutaneous microwave ablation. The treatment effect, liver function indicators and occurrence complications were compared between the two groups. ResultsThere was no statistically significant difference in the treatment effect between the two groups (P>0.05). The levels of total bilirubin (TBil), alanine aminotransferase (ALT) and aspartate aminotransferase (AST) between the two groups had no significant difference before operation (all P>0.05). After operation, the levels of TBil, ALT and AST in both groups were lower than those before operation, which were lower in the observation group than in the control group (all P<0.05). The incidence of complications in the observation group was 5.00%, which was lower than that in the control group (22.50%) (P<0.05). ConclusionIn the treatment of hepatic hemangioma, ultrasound-guided percutaneous microwave ablation can achieve a comparable efficacy with open laparotomy and is more beneficial for improving patients′ liver function and reducing the incidence of complications, which is worthy of wide clinical application.