微创医学

目的通过Meta分析系统评价颅内压监测对脑出血患者病死率的影响。方法通过计算机检索中国知网、万方数据知识服务平台、维普数据库、PubMed、Cochrane等数据库，纳入有关研究颅内压监测对自发性脑出血患者病死率影响的文献。提取数据并进行文献质量评价后，采用RevMan 5.4软件对符合标准的文献进行Meta分析。结果共纳入13篇文献（5篇为随机对照研究，8篇为队列研究），包括4 035例患者。Meta分析结果显示，治疗组和对照组的病死率差异无统计学意义［OR=0.53（95% CI：0.25，1.14)，P=0.11］。结论颅内压监测不能降低自发性脑出血患者的病死率，其在自发性脑出血患者治疗中的作用有待进一步研究。

ObjectiveTo systematically evaluate the effect of intracranial pressure monitoring on the fatality rate of patients with spontaneous cerebral hemorrhage by Meta-analysis. MethodsDatabases such as CNKI, Wanfang Data Knowledge Service Platform, VIP Database, PubMed, Cochrane, etc. were searched by the computer to include articles about the effect of intracranial pressure monitoring on the fatality rate of patients with spontaneous cerebral hemorrhage. After data extraction and literature quality evaluation, the Revman 5.4 software was used to conduct Meta-analysis on the eligible articles. ResultsTotally 13 articles (5 randomized controlled studies and 8 cohort studies) were included, with 4 035 patients. The results of Meta-analysis showed that there was no statistically significant difference in the fatality rate between the treatment group and the control group ［OR=0.53, (95% CI:0.25, 1.14), P=0.11］. ConclusionIntracranial pressure monitoring cannot reduce the fatality rate of patients with spontaneous cerebral hemorrhage, and its effect on the treatment of patients with spontaneous cerebral hemorrhage needs further study.

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