ObjectiveTo analyze the clinical value of ultrasonography in the diagnosis of precocious puberty in girls. MethodsA total of 70 girls with suspected precocious puberty were selected into the experimental group, and 70 healthy girls examined in outpatient department at the same time were selected into the control group. Both groups underwent ultrasonography. Taking the results of gonadotropin-releasing hormone (GnRH) stimulation test as the gold standard, the accuracy, sensitivity, and specificity of ultrasonography in the diagnosis of girls′ precocious puberty were calculated, and the consistency between ultrasonography and GnRH stimulation test was examined by Kappa test. Girls with precocious puberty were included in the precocious puberty group, and girls without precocious puberty in the non-precocious puberty group. The ovarian and uterine ultrasonic detection indexes, as well as the thickness of mammary hypoechoic mass between the two groups were compared. ResultsThe accuracy, sensitivity, and specificity of ultrasonography in the diagnosis of precocious puberty in girls were 92.86 %, 94.03% and 66.67%, respectively. The ultrasonography and GnRH stimulation test showed a good consistency (Kappa value=0.785). In the precocious puberty group, the ovarian length, transverse diameter, ovarian volume, and maximum diameter of follicles, as well as the uterine longitudinal diameter, transverse diameter, anteroposterior diameter and volume, and the thickness of mammary hypoechoic mass were greater than those in the non-precocious puberty group (all P＜0.05). ConclusionThe diagnosis of precocious puberty in girls by ultrasonography is consistent with the gold standard, and has high diagnostic accuracy, specificity and sensitivity. Moreover, ultrasonography can provide ovarian, uterine, and mammary ultrasound indexes, and can be used to guide clinical treatment plan.

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