微创医学

目的探讨瑶医神火灸联合玻璃酸钠注射治疗老年性膝骨关节炎（KOA）的临床疗效。方法将150例老年性KOA患者随机分为治疗组、对照1组、对照2组，每组50例。治疗组采用瑶医神火灸联合玻璃酸钠注射治疗，对照1组采用单纯神火灸治疗，对照2组采用玻璃酸钠注射治疗。比较3组患者治疗前后膝关节液中白细胞介素-1（IL-1）水平、肿瘤坏死因子-α（TNF-α）水平，Lysholm膝关节功能量表评分及临床疗效。结果治疗后,3组患者的IL-1、TNF-α水平均较治疗前低，且治疗组上述指标水平低于对照1组和对照2组（均P＜0.05），而对照1组和对照2组IL-1、TNF-α水平差异无统计学意义（P＞0.05）。治疗后，3组Lysholm膝关节功能量表评分均较治疗前高，且治疗组评分高于对照1组和对照2组（均P＜0.05），而对照1组和对照2组评分差异无统计学意义（P＞0.05）。治疗组的临床疗效优于对照1组和对照2组（均P＜0.05），而对照1组和对照2组比较，差异无统计学意义（P＞0.05）。结论采用瑶医神火灸联合玻璃酸钠治疗老年KOA疗效显著，可减轻炎症反应，改善患者膝关节功能，为中西结合防治KOA提供新思路。

ObjectiveTo investigate the clinical efficacy of Yao Medicine shenhuo moxibustion combined with sodium hyaluronate injection in the treatment of senile knee osteoarthritis (KOA). MethodsA total of 150 patients with senile KOA were randomly divided into treatment group, control group 1 or control group 2, with 50 cases in each group. The treatment group was treated with Yao Medicine shenhuo moxibustion combined with sodium hyaluronate injection, the control group 1 was treated with simple shenhuo moxibustion, and the control group 2 was treated with sodium hyaluronate injection. The levels of interleukin-1 (IL-1) and tumor necrosis factor-α (TNF-α) in the knee joint fluid, and the Lysholm knee function scale score before and after treatment, as well as the clinical efficacy were compared between the 3 groups. ResultsAfter treatment, the levels of IL-1 and TNF-α in the 3 groups were lower than those before treatment, and the above index levels in the treatment group were lower than those in the control group 1 and control group 2 (all P＜0.05). There was no statistically significant difference in the levels of IL-1 and TNF-α between the control group 1 and control group 2 (P＞0.05). After treatment, the scores of Lysholm knee joint function scale in the 3 groups were all higher than those before treatment, and the score in the treatment group was higher than that in the control group 1 and control group 2 (all P＜0.05), but there was no statistically significant difference in the scores between the control group 1 and control group 2 (P＞0.05). The clinical efficacy of the treatment group was better than that of the control group 1 and the control group 2 (all P＜0.05), while there was no significant difference between the control group 1 and the control group 2 (P＞0.05).ConclusionYao Medicine shenhuo moxibustion combined with sodium hyaluronate is effective in treating senile KOA, which can reduce the inflammatory reaction and improve the knee joint function of patients and provide a new idea for the prevention and treatment of KOA by integrating traditional Chinese and western medicine.