ObjectiveTo explore the safety and effectiveness of transjugular intrahepatic portosystemic shunt (TIPS) combined with AngioJet thrombus remover for treating acute non-neoplastic portal vein thrombosis (PVT) in cirrhosis. MethodsThe clinical and imaging data of 9 patients with acute non-neoplastic PVT in cirrhosis, who received TIPS combined with AngioJet thrombus remover for treatment, were retrospectively analyzed. The baseline information was analyzed, and the clearance degree of main venous thrombosis immediately after operation and 6 months after operation, complications during the treatment, and the stent patency rate 6 months after operation were observed. ResultsAll 9 patients were successfully treated, thereinto there were 6 cases (66.67%), whose clearance degree of main venous thrombosis expressed in grade Ⅱ immediately after operation, and 3 cases (33.33%) interpreted in grade Ⅲ of clearance degree of main venous thrombosis. A total of 7 cases occurred hemoglobinuria after operation, who returned to normal after the treatment of hydrates and alkalized urine 1-2 days; moreover, one case occurred slighter blood exudation at puncture point, which hemostasis after compression bandaging; furthermore, one patient occurred hepatic encephalopathy, whose symptoms disappeared after drug treatment; in addition, no serious complication including intestinal necrosis, alimentary rehemorrhage etc. occurred in all patients. The stents were unobstructed at 6 months of follow-up, with 100.00% patency rate. A total of 4 cases (44.44%) interpreted in grade Ⅱ of the clearance of portal vein system, and 5 cases (55.56%) in grade Ⅲ. No clinical symptom reoccurred. ConclusionTIPS combined with AngioJet thrombus remover for the treatment of acute non-neoplastic PVT in cirrhosis is safe and effective, which is worthy of clinical promotion.

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