目的观察Quadrant通道辅助下微创经椎间孔腰椎椎间融合术(MIS-TLIF)对单节段性腰椎病变患者的疗效。方法选择60例单节段性腰椎病变患者,随机分为观察组(30例,行Quadrant通道辅助下MIS-TLIF)和对照组(30例,行传统开放手术)。比较两组患者的围术期相关指标、肌酸激酶(CK)水平、T2弛豫时间、Oswestry功能障碍指数(ODI)、腰痛及腿痛VAS评分和并发症发生率。结果两组患者手术时间比较差异无统计学意义(P>0.05);观察组术中失血量、术后引流量、住院天数均少/短于对照组(均P<0.05)。术后3 d,观察组CK水平低于对照组(P<0.05)。术后3个月,观察组T2弛豫时间短于对照组,ODI评分、腰痛及腿痛VAS评分低于对照组(均P<0.05)。观察组并发症发生率(3.33%)与对照组(13.33%)比较,差异无统计学意义(P>0.05)。结论对单节段性腰椎病变患者行Quadrant通道辅助下MIS-TLIF,手术创伤小,能促进患者快速康复,并发症发生风险低,值得推广。
ObjectiveTo observe the efficacy of minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) assisted by Quadrant channel on patients with single segment lumbar disease. MethodsA total of 60 patients with single segment lumbar disease were selected and randomly assigned to observation group (30 cases, undergoing MIS-TLIF assisted by Quadrant channel), and control group (30 cases, undergoing conventional open surgery). The perioperative related indices, creatine kinase (CK) level, T2 relaxation time, Oswestry dysfunction index (ODI), VAS scores of lumbargo and skelalgia, and incidence of complications were compared between the two groups. ResultsThe difference of operation duration was not statistically significant between the two groups (P>0.05); moreover, the observation group yielded less intraoperative bleeding volume, postoperative drainage volume, and shorter hospital stays as compared with the control group (all P<0.05). The observation group obtained lower CK level 3 days after operation, shorter T2 relaxation time, lower scores of ODI, and VAS of lumbargo and skelalgia 3 months after operation in comparison of the control group (all P<0.05). There was no statistically significant difference in the incidence of complications between the observation group and the control group (3.33% vs. 13.33%, P>0.05). ConclusionEmploying MIS-TLIF assisted by Quadrant channel on patients with single segment lumbar disease has slight operative trauma, and it can promote rapid recovery of patients, with low prevalence of complications. Thus it is worthy of promotion.