ObjectiveTo evaluate the safety and clinical effects of ACUSEAL early cannulation graft in the pathway of upper extremity hemodialysis. MethodsClinical data of 90 patients underwent upper extremity arteriovenous graft (AVG) established by artificial blood vessel as the pathway of hemodialysis were retrospectively analyzed. The patients were assigned to ACUSEAL group (employing ACUSEAL early cannulation graft, n=32), and the INTERING group (employing INTERING vascular graft, n=58) according to the selected types of artificial blood vessel. The first puncture time after operation, postoperative dialysis blood flow were compared between the two groups. One-year follow-up after operation, primary and secondary patency of artificial blood vessels, and complications of artificial blood vessel were evaluated in the two groups. ResultsThe successful rate of operative technology was 100%. The postoperative first puncture time was shorter in the ACUSEAL group than in the INTERING group (P＜0.05). There were no statistically significant differences in the portion of forearm fistula, postoperative dialysis blood flow, the primary and secondary patency of artificial blood vessels one-year follow-up after operation between the two groups (all P＞0.05) . A total of 22 patients had AVG dysfunction one year of follow-up, among which 13 cases had AVG dysfunction induced by infection, 6 cases had AVG dysfunction induced by thrombosis, one case because of pseudoaneurysm formation, one case because of steal bloocl syndrome,and one case had dysfunction because of artificial blood vessel stratification. No death case related to operation occurred in the two groups. There were no statistically significant differences in the complications incidence of artificial blood vessel (all P＞0.05). ConclusionEmploying ACUSEAL early cannulation graft to fistulization can be performed graft in the early stage, with high patency, less complications. It has relatively good clinical application effects in the pathway of hemodialysis.

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