ObjectiveTo investigate the influencing factors for the occurrence of macular edema (ME) in patients with diabetic cataract after phacoemulsification combined with implantation of artificial lens. MethodsA total of 80 patients with diabetic cataract who underwent phacoemulsification combined with implantation of artificial lens were selected, and they were assigned to groups based on the occurrence of ME after surgery. The baseline information were collected, and the levels of serum total cholesterol (TC), triglyceride (TG), glycosylated hemoglobin (HbA1c), vascular endothelial growth factor (VEGF), as well as the interleukin-6 (IL-6) in aqueous humor were detected in both groups. The influencing factors for the occurrence of ME after phacoemulsification combined with implantation of artificial lens in patients with diabetic cataract were analyzed. ResultsAmong 80 patients with diabetic cataract after phacoemulsification combined with implantation of artificial lens, 23 cases (28.75%) occurred ME (the occurrence group) after surgery, whereas 57 cases(71.25%) did not occur ME (the non-occurrence group). The levels of HbA1c, VEGF and IL-6 in the occurrence group were higher than those in the non-occurrence group (all P＜0.05). There were no statistically significant differences in gender, age, duration of diabetes, hypertension, TC, and TG between the two groups (all P＞0.05). Multivariate logistic regression analysis showed that high expressions of HbA1c, VEGF and IL-6 were the independent risk factors for the occurrence of ME after phacoemulsification combined with implantation of artificial lens in patients with diabetic cataract (all P＜0.05). ConclusionThe occurrence of ME after phacoemulsification combined with implantation of artificial lens in patients with diabetic cataract is influenced by the levels of HbA1c, VEGF and IL-6.

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