ObjectiveTo investigate the effects of emergency coronary intervention on N-terminal pro-B-type natriuretic peptide (NT-proBNP) and left ventricular remodeling in the treatment of patients with acute myocardial infarction. MethodsA total of 60 patients with acute myocardial infarction were selected and randomly assigned to control group (n=30) and research group (n=30). The control group received routine treatment, based on which the research group received the combined treatment of emergency coronary intervention. The pre- and post-treatment NT-proBNP levels, left ventricular end-systolic diameter (LVESD) and left ventricular ejection fraction (LVEF), and left ventricular end-diastolic diameter (LVEDD) were compared between the two groups, and the conditions of left ventricular remodeling were observed in the two groups. ResultsThere was a statistically significant difference in level of NT-proBNP (Fgroup=14.453, Pgroup=0.002), the level of NT-proBNP in both groups had a tendency to decrease over time (Ftime=16.694, Ptime=0.002), and the grouping interacted with time (Finteraction=9.962, Pinteraction=0.019). Among them, the research group yielded lower level of NT-proBNP after 1, 2, 3 days of treatment as compared with the control group (all P＜0.05). Compared to before treatment, LVESD and LVEDD in both groups more reduced, whereas LVEF more increased at 3 days of treatment, and the research group yielded more significant decrease of LVESD and LVEDD, while more significant increase of LVEF as compared with the control group (all P＜0.05). ConclusionEmergency coronary intervention can effectively decrease the levels of NT-proBNP in patients with acute myocardial infarction, improve myocardial function in patients, and inhibit left ventricular remodeling.

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