ObjectiveTo investigate the influence of laparoscopic gastric wedge resection on the prognosis and immune function of patients with gastric stromal tumors. MethodsA total of 82 patients with gastric stromal tumor were selected and assigned to two groups according to the randomized parallel control method, 41 patients in the control group received open gastric wedge resection, while 41 patients in the observation group received laparoscopic gastric wedge resection. Perioperative related indexes, prognostic indexes and immune function indexes were observed and compared between the two groups. ResultsThe observation group yielded a less intraoperative blood loss and smaller wound diameter, and lower systolic blood pressure as compared with the control group (all P＜0.05). After treatment, the levels of albumin and high density lipoprotein cholesterol (HDL-C) of both groups increased, the values of fibrinogen to albumin ratio index (FARI), and the fibrinogen levels decreased compared with before treatment, and the observation group yielded more significant changes in the indicators as above as compared with the control group (all P＜0.05). After treatment, both groups obtained significantly higher levels of CD4+/CD8+、CD3+ T and CD4+ T cells to compare with before treatment, and the indicators mentioned above in the observation group were higher than those in the control group (all P＜0.05). ConclusionLaparoscopic gastric wedge resection has a significant effect on gastric stromal tumors, which has a small wound, less bleeding, less pain and rapid recovery of intestinal function. It can shorten the fasting time in patients, increase the immunity of body, and facilitate the prognosis of patients.

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