微创医学

目的探讨对急性胆源性胰腺炎（ABP）患者行内镜逆行胰胆管造影(ERCP)手术的临床效果。方法利用电脑随机数将100例ABP患者分为对照组（n=50）与试验组（n=50），其中对照组给予内科保守治疗，试验组行ERCP手术治疗。比较两组患者的临床疗效、腹痛缓解时间、白细胞计数恢复正常时间、血淀粉酶恢复正常时间、住院时间，以及治疗前后炎症因子及肝功能指标水平。结果试验组患者的临床疗效明显优于对照组（P＜0.05）。试验组腹痛缓解时间、白细胞计数恢复正常时间、血淀粉酶恢复正常时间及住院时间与对照组比较均明显缩短（均P＜0.05）。治疗后两组患者的炎症因子水平均较治疗前显著降低，且试验组低于对照组（均P＜0.05）。治疗后两组肝功能指标均较治疗前改善，且试验组改善程度优于对照组（均P＜0.05）。结论应用ERCP手术治疗ABP的临床效果佳，能有效缩短患者临床症状恢复时间，改善肝功能，减轻炎症反应。

ObjectiveTo explore the clinical effects on patients with acute biliary pancreatitis (ABP) undergoing endoscopic retrograde cholangiopancreatography (ERCP). MethodsA total of 100 ABP patients were assigned to control group (n=50) and study group (n=50) by the computer random number, among which the control group received medical therapy, whereas the study group underwent ERCP for treatment. The clinical efficacy, relief time of abdominal pain, time for the white blood cell counts to return to normal, time for the blood amylase to return to normal, hospital stays, and pre- and post-treatment indexes levels of inflammatory factors and liver function were compared between the two groups. ResultsThe clinical efficacy of the study group was significantly superior to that of the control group (P＜0.05). Compared with the control group, the study group yielded significantly shorter relief time of abdominal pain, time for the white blood cell counts to return to normal, time for the blood amylase to return to normal, and hospital stays (all P＜0.05). The inflammatory factors levels significantly decreased after treatment than before treatment, and the levels were lower in the study group than in the control group (all P＜0.05). Compared to before treatment, the liver function indexes improved after treatment, and the improvement of the indexes were superior to the study group than to the control group (all P＜0.05). ConclusionEmploying ERCP in the treatment of ABP has good clinical effects, which can effectively shorten recovery time for clinical symptoms, improve the liver function, and alleviate inflammatory responses.