ObjectiveTo investigate the clinical efficacy of percutaneous endoscopic nucleus pulposus removal in the treatment of lumbar disc herniation and its effects on prognosis. MethodsA total of 104 patients with lumbar disc herniation were selected, and they were randomly divided into control group and study group, with 52 cases in each group. The control group was treated with traditional open resection of nucleus pulposus, while the study group was treated with percutaneous endoscopic nucleus pulposus removal. The therapeutic effect, perioperative clinical indexes, as well as the pre- and postoperative stability of lumbar vertebra, and prognosis were compared between the two groups. ResultsThe good rate of the study group was significantly superior to that of the control group (P＜0.05). The study group yielded shorter time of operation and postoperative in-bed, and less intraoperative bleeding volume as compared with the control group (all P＜0.05). Both groups yielded larger lumbar curvature index, intervertebral angle changes and intervertebral horizontal displacement, whereas a smaller vertebral Cobb angle 6 months after operation as compared with before operation (all P＜0.05). After 6 months of operation, the study group yielded smaller vertebral Cobb angle, intervertebral angle changes, and intervertebral horizontal displacement, whereas larger lumbar curvature index in the comparison of the control group (all P＜0.05). Six months after operation, the Japanese Orthopaedic Association (JOA) scores in both groups increased, and the score in the study group was higher than that in the control group (all P＜0.05). ConclusionPercutaneous endoscopic nucleus pulposus removal for patients with lumbar disc herniation can effectively maintain the stability of the lumbar vertebra, improve clinical efficacy, and the operation duration is short, intraoperative bleeding volume is minimal, with a high safety; furthermore, the prognosis of patients is preferable, and it is worthy of clinical promotion.

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