目的观察中药联合针灸辅助治疗应用于呼吸机依赖患者的临床效果。方法选择呼吸机依赖患者120例,利用随机数字表法将患者分为观察组和对照组,各60例。对照组予常规肺功能恢复治疗以促进患者顺利完成脱机,观察组在对照组治疗的基础上加用中药联合针灸辅助治疗以促进患者顺利完成脱机。记录并比较两组患者的撤机成功率、呼吸机相关性肺炎(VAP)发生率、ICU住院时间、呼吸机使用时间,以及治疗前后患者心率、自主呼吸频率和动脉血气分析指标。结果观察组患者的呼吸机撤机成功率高于对照组,VAP发生率低于对照组,呼吸机使用时间、ICU住院时间均短于对照组(均P<0.05)。治疗后,两组心率、自主呼吸频率均较治疗前明显降低,两组动脉血氧分压(PaO2)、动脉血二氧化碳分压(PaCO2)均较治疗前明显升高,且观察组上述指标均优于对照组(均P<0.05)。结论中药联合针灸辅助治疗呼吸机依赖患者的脱机困难,有助于更好地促进患者呼吸功能恢复,改善患者对呼吸机的依赖,预防呼吸机相关并发症,明显提高脱机成功率,缩短上机时间。
ObjectiveTo observe the clinical effects of adjuvant therapy of traditional Chinese medicine combined with acupuncture in the application of ventilator-dependent patients. MethodsA total of 120 patients with ventilator dependence were selected and divided into observation group and control group by the random number table method, with 60 cases in each group. In order to facilitate the patients successfully off the ventilator, routine therapy of pulmonary function recovery was conducted in the control group, based on which the observation group additionally received adjuvant therapy of traditional Chinese medicine combined with acupuncture. The success rate of ventilator weaning, the incidence of ventilator-associated pneumonia (VAP), ICU stays, time of ventilator use, and the pre- and post-treatment heart rate, spontaneous breathing frequency, and arterial blood gas analysis indicators were record and compared between the two groups. ResultsCompared with the control group, the observation group yielded higher success rate of ventilator weaning, lower incidence of VAP, and shorter time of ventilator use and ICU hospitalization (all P<0.05). After treatment, both groups obtained significantly lower heart rate and spontaneous breathing frequency, whereas significantly higher arterial partial pressure of oxygen (PaO2) and arterial partial pressure of carbon dioxide (PaCO2) in the comparison of before treatment, and the indicators mentioned above in the observation group were superior to those in the control group (all P<0.05). ConclusionTraditional Chinese medicine combined with acupuncture in the adjuvant treatment of ventilator weaning difficulties in ventilator-dependent patients is helpful to facilitate recovery of respiratory function, improve the dependence to ventilator, prevent ventilator-associated complications in patients. It can increase the success rate of ventilator weaning, and shorten the time of ventilator use.