ObjectiveTo investigate the application value of percutaneous atrial septal defect closure guided by trans-esophageal echocardiography. MethodsA total of 40 patients with atrial septal defect undergoing occlusion were selected and divided into control group and observation group according to the random number table method, with 20 cases in each group. Among which the observation group was treated with percutaneous atrial septal defect closure guided by trans-esophageal echocardiography, while the control group was treated with minimally invasive atrial septal defect closure via thoracic approach guided by trans-esophageal echocardiography. The success rate of occlusion, operation time, endotracheal intubation time and hospital stays were compared between the two groups. The patients were followed up for 1 year, and the postoperative complications of the two groups were recorded. ResultsThe success rate of occlusion in both groups was 100%, but the operation time, endotracheal intubation time and hospital stays in the observation group were significantly shorter than those in the control group (all P＜0.05). The total incidence of postoperative complications in the observation group was significantly lower than that in the control group (5.0% vs. 35.0%, P＜0.05). ConclusionCompared with minimally invasive arterial septal defect closure via thoracic approach guided by trans-esophageal echocardiography, percutaneous atrial septal defect closure guided by trans-esophageal echocardiography is more safe, reliable and has a superior effect. There is no need for expensive, large imaging equipment, which is especially suitable for the medical institutions in basic level and underdeveloped areas with backward medical hardware equipment, and it is convenient to implement and has good feasibility and high promotion value.

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