目的分析经阴道手术治疗剖宫产瘢痕部位妊娠(CSP)的临床效果。方法选取CSP患者78例,采用随机数字表法将其分为对照组(n=39,行宫腔镜下清宫及瘢痕妊娠病灶电切术)和观察组(n=39,经阴道手术)。比较两组治疗效果、手术相关指标及血清β-人绒毛膜促性腺激素(β-hCG)水平。结果观察组的治疗成功率为97.44%,高于对照组的74.36%(P<0.05)。观察组手术时间长于对照组,术中出血量、住院费用、住院时间少/短于对照组 (均P<0.05)。术后1 d、3 d、7 d、14 d观察组的血清β-hCG水平均低于对照组 (F组间=6 239.000,P组间<0.001),两组的血清β-hCG水平均有随时间变化而降低的趋势(F时间=167.300,P时间<0.001),分组与时间有交互效应(F交互=75.040,P交互<0.001)。结论经阴道手术治疗CSP的临床效果显著,能够快速使血清β-hCG水平降至正常,手术治疗成功率高,具有较高的临床应用价值。
ObjectiveTo analyze the clinical effects of transvaginal surgery in treating cesarean scar pregnancy (CSP). MethodsA total of 78 CSP patients were selected, and they were divided into control group (n=39, undergoing evacuation of uterus via hysteroscope and scar pregnancy electrical resection of the lesions) and observation group (n=39, undergoing transvaginal surgery) by the random number table method. The therapeutic effect, surgical related indicators and serum β-human chorionic gonadotropin (β-hCG) level were compared between the two groups. ResultsThe treatment success rate in the observation group was 97.44%, which was higher than that in the control group (74.36%) (P<0.05). The observation group yielded longer surgery duration, whereas less intraoperative blood loss volume and hospital expenses, and shorter hospital stays (all P<0.05). After 1 d, 3 d, 7 d and 14 d of surgery, the serum β-hCG level in the observation group was lower than that in the control group (Fintergroup=6 239.000, Pintergroup<0.001), and the serum β-hCG level in both groups interpreted a trend of decreasing over time (Ftime=167.300, Ptime<0.001). The grouping had interaction effect with time (Finteraction=75.040, Pinteraction<0.001). ConclusionTransvaginal surgery for CSP has a significant clinical effect, which can quickly decrease serum β-hCG to the normal level, and improve the success rate of surgery, and thus it has a high clinical application value.