ObjectiveTo investigate the clinical value of fast track surgery (FTS) concept combined with laparoscopic technique applied to colorectal cancer surgery. MethodsA total of 100 patients with colorectal cancer were randomly divided into observation group and control group, with 50 cases in each group. Patients in the observation group employed FTS concept combined with laparoscopic surgery, while patients in the control group used FTS concept combined with open surgery. The operation duration, intraoperative blood loss volume, incision length, number of lymph nodes dissection, and the stress reaction indexes ［white blood cell (WBC) counts, C-reactive protein (CRP), interleukin 6 (IL-6)］, cells immune indexes ( CD3+, CD4+ and CD4+/CD8+) before and after operation, and postoperative recovery time of intestinal peristalsis, the first exhaust time and defecation time, postoperative complications incidence, hospital stays, hospital expenses were compared between the two groups. ResultsCompared with the control group, the observation group yielded less intraoperative blood loss volume, a shorter incision length, shorter postoperative recovery time of intestinal peristalsis, whereas higher hospital expenses (all P＜0.05). After 1 d, 3 d, and 5 d of operation, the WBC counts, levels of CRP and IL-6 in the two groups increased as compared with before operation (all P＜0.05). After 1 d of operation, the observation group yielded lower WBC counts, levels of CRP and IL-6 as compared with the control group (all P＜0.05). After 3 d of operation, the levels of CRP and IL-6 in the observation group were lower than those in the control group (all P＜0.05), but there were no statistically significant differences of WBC counts between the two groups (P＞0.05). After 5 d of operation, the CRP level was lower in the observation group than in the control group (P＜0.05), but there were no statistically significant differences in WBC counts and IL-6 level (all P＞0.05). There were no statistically significant differences in operation duration, number of lymph nodes dissection, the first exhaust time and defecation time, cells immune indexes, postoperative hospital stays and complications between the two groups (all P＞0.05). ConclusionLaparoscopic colorectal cancer surgery via the guidance of FTS concept can effectively reduce perioperative trauma and stress response, inhibit the release of postoperative inflammatory factors, provide good protection for postoperative cellular immunity, and accelerate postoperative recovery of patients to a certain extent, which is worthy of promotion and application.

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