目的比较胸腔镜联合腹腔镜手术与传统三切口手术治疗高龄中下段食管癌患者的临床效果。方法纳入100例高龄食管癌患者,其中接受胸腔镜联合腹腔镜手术治疗的50患者为观察组,接受传统三切口手术治疗且一般资料与观察组均衡可比的50例患者为对照组。比较两组患者的手术时间、术中出血量、术后第1天引流量、血红蛋白下降量、住院天数、淋巴结清扫情况、术后并发症及随访情况。结果观察组患者的手术时间、住院天数短于对照组,术中出血量、术后第1天引流量少于对照组,血红蛋白下降量大于对照组(均P<0.05)。观察组患者上纵隔淋巴结、中下纵隔淋巴结、腹腔淋巴结清扫数量均大于对照组(均P<0.05)。两组患者的颈部淋巴结清扫数量比较,差异无统计学意义(P>0.05)。观察组并发症发生率低于对照组(P<0.05)。两组疾病转移率、复发率比较,差异无统计学意义(均P>0.05)。结论对高龄食管癌患者行胸腔镜联合腹腔镜手术较传统食管三切口术的创伤更小,淋巴结清扫更彻底,术后恢复更快,预后更优,能取得更好的临床效果。
ObjectiveTo compare the clinical effects of thoracoscopic combined with laparoscopic surgery with traditional three-incision surgery in treating senile patients with middle and lower esophageal cancer. MethodsA total of 100 senile patients with esophageal cancer were enrolled, among which 50 patients received thoracoscopic combined with laparoscopic surgery for treatment were assigned to observation group, whereas 50 patients received traditional three-incision surgery, and whose general data were equitably comparable with the observation group, were assigned to control group. The surgery duration, intraoperative blood loss volume, drainage volume on the first day after surgery, volume of hemoglobin decline, hospital stays, lymph nodes dissection, complications after surgery and follow-up conditions were compared between the two groups. ResultsThe observation group yielded shorter surgery duration and hospital stays, lower volume of intraoperative blood loss and drainage on the first day after surgery, whereas larger volume of hemoglobin decline as compared with the control group (all P<0.05). Compared to the control group, patients in the observation group obtained larger numbers of lymph nodes dissection in upper mediastinal lymph nodes, middle and lower mediastinal lymph nodes, and abdominal lymph nodes (all P<0.05). There was no statistically significant difference in the number of lymph nodes dissection in cervical lymph nodes between the two groups (P>0.05). The incidence of complications was lower in the observation group than in the control group (P<0.05). There were no statistically significant differences in disease metastasis and recurrence between the two groups (all P>0.05). ConclusionCompared to traditional three-incision of esophageal surgery, employing thoracoscopic combined with laparoscopic surgery has less trauma, more radical numbers of lymph nodes dissection, faster recovery after surgery, superior prognosis, and better clinical effect.