ObjectiveTo explore the application effects of ultrasound-guided transversus abdominis plane block combined with rectus sheath block in perioperative analgesia during radical resection of colorectal cancer. MethodsA total of 120 patients received radical resection of colorectal cancer for treatment were selected, and they were assigned to control group (60 cases) and observation group (60 cases) according to the random number table method, among which patients in the control group were conducted with ultrasound-guided transversus abdominis plane block, whereas the observation group was conducted with ultrasound-guided transversus abdominis plane block combined with rectus sheath block. The heart rate, mean arterial pressure, and the VAS scores in various time points, as well as the incidence of complications were compared between the two groups. ResultsThere were no statistically significant differences in the heart rate, mean arterial pressure before anesthesia induction (T0), at the beginning of operation (T1), and 1 h after operation (T2) between the two groups (all P＞0.05). The observation group yielded lower levels of heart rate and mean arterial pressure 15 min after extubation（T3）, and lower VAS scores at the time of leaving anesthesia recovery room, and 4 h, 12 h, 24 h after operation as compared with the control group (all P＜0.05). Compared to the control group, the observation group yielded a lower incidence of dizziness, drowsiness, and nausea and vomiting (all P＜0.05). ConclusionUltrasound-guided transversus abdominis plane block combined with rectus sheath block can maintain the postoperative heart rate and mean arterial pressure stable in patients with colorectal cancer after raclical resection, relieve postoperative pain, and also decrease the incidence of complications, with a significant clinical effect.

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