目的探索前列腺增生(BPH)患者肾功能损害与膀胱残余尿相关性。方法回顾性分析接受手术治疗并经病理证实为单纯BPH的病例441例,分成A组138例(残余尿量<12 mL),B组127例(残余尿量12~50 mL),C组51例(残余尿量50~200 mL),D组126例(残余尿>200 mL)。对四组患者的血肌酐、残余尿作对照研究。结果 A、B、C、D组的血肌酐分别为(98.23±42.00)μmol/L、(121.39±82.93)μmol/L、(67.15±24.78)μmol/L和(156.15±146.38)μmol/L,差异均有统计学意义。结论随着膀胱残余尿量的增多,BPH患者肾功能损害有加重趋势。
Objective To study the relationship between bladder residual urine volume and renal function lesion in patients with benign prostatic hyperplasia( BPH) . Methods Clinical data of 441 BPH were studied retrospectively. All the cases were divided into 4 groups: group A( 138 cases,the residual urine volume < 12 ml) , group B( 127 cases,the residual urine volume 12 - 50 ml) , group C( 50 cases,the residual urine volume50 - 200 ml) , and group D( 126 cases,the residual urine volume > 200 ml) . Blood serum creatinine ( Cr) and urea niteogen( BUN) were observed and compared among the four groups. Results The serum Cr in group A,group B,group C,and group D were ( 98. 23 ± 42. 00 ) μmol /L,( 121. 39 ± 82. 93 ) μmol /L, ( 67. 15 ± 24. 78) μmol /L,and( 156. 15 ± 146. 38) μmol /L, respectively. There existed statistical significant difference among all four groups. Conclusion Renal function impairment worsens with the increase of bladder residual urine volume in patients with BPH.