ObjectiveTo investigate the clinical effect of laparoscopic myomectomy and its effect on stress response in patients with hysteromyoma. MethodsClinical data of 96 patients with hysteromyoma were analyzed retrospectively. Patients were divided into traditional group or minimally invasive group according to their operation methods, with 48 cases in each group. The traditional group was treated with open surgery of myomectomy, while the minimally invasive group was treated with laparoscopic myomectomy. The operative index, condition of recovery, stress response index, and the incidence of complications during treatment were compared between the two groups. ResultsCompared to the traditional group, the minimally invasive group had significantly longer operation duration, but significantly less intraoperative blood loss, time of postoperative exhaust and defecation, and hospital stay (all P＜0.05). After operation, the levels of norepinephrine(NE), substance P(SP), epinephrine(E) increased significantly in both groups, with the levels lower in the minimally invasive group than in the traditional group, while the level of glutathione peroxidase (GSH-Px) decreased significantly in both groups, with the level was significantly higher in the minimally invasive group than in the traditional group (all P＜0.05). The incidence of complications in the minimally invasive group was 4.17%, which was significantly lower than 20.83% in the traditional group (all P＜0.05). ConclusionThe application of laparoscopic technique in the treatment of hysteromyoma is associated with less intraoperative blood loss, faster postoperative recovery. It can obviously alleviate the stress response of patients, and reduce the incidence of complications. It is worthy of clinical promotion.

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