目的探讨益气活血方对冠心病介入术后患者心脏康复的影响。方法选择150例因冠心病行经皮冠状动脉介入治疗(PCI)的患者,按随机数字表法分为对照组和研究组,各75例。对照组予常规西药治疗,研究组在对照组治疗基础上加服益气活血方,疗程3个月,随访6个月。分别记录两组患者入院时、出院后2个月、出院后6个月的生活质量量表(SF-36)评分及中医证候评分;记录入院时、出院后6个月的心功能评价指标结果;比较两组患者随访期间主要心脏不良事件发生率。结果出院后2个月、6个月两组患者的SF-36量表评分均较入院时降低(均P<0.05),出院后6个月,研究组的SF-36量表评分明显低于对照组(P<0.05)。出院后6个月,两组患者的左室舒张末期内径(LVEDD)、左室收缩末期内径(LVESD)、每搏输出量(SV)、左室射血分数(LVEF)均较入院时明显改善(均P<0.05),且研究组较对照组更明显(P<0.05)。出院后两组患者的中医证候积分均较入院时升高,且研究组较对照组更为明显(均P<0.05)。两组均未出现明显的不良反应。结论益气活血方能够改善PCI术后康复期患者的心功能和远期生命质量。
ObjectiveTo explore the effect of Yiqi Huoxue decoction on the cardiac rehabilitation in coronary heart disease patients after percutaneous coronary intervention. MethodsA total of 150 patients with coronary heart disease underwent percutaneous coronary intervention (PCI) were selected and divided into control group or study group according to random number table method, with 75 cases in each group. Both groups were administered conventional western medicine, whereas the study group was treated with Yiqi Huoxue decoction additionally, with three-month treatment and six-month follow-up. The Short Form 36-item Health Survey (SF-36) score and traditional Chinese medical syndrome score were recorded at the time of hospital admission, 2 months and 6 months after discharge, respectively.The result of cardiac function evaluation indexes were recorded at the time of hospital admission and 6 months after discharge. The incidence of major adverse cardiac events was compared between the two groups. ResultsCompared to the time of hospital admission, the score of SF-36 were decreased 2 and 6 months after discharge in both groups (all P<0.05), and 6 months after discharge, the score of SF-36 was significantly lower in the study group than in the control group (P<0.05). Six months after discharge, left ventricular end diastolic diameter(LVEDD), left ventricular end systolic diameter(LVESD), stroke volume(SV), left ventricular ejection fraction(LVEF) of the two groups were significantly improved (all P<0.05), and the changes were more obvious in the study group (P<0.05). After discharge, the traditional Chinese medical syndrome scores of the two groups were increased, with the increase more significant in the study group (all P<0.05). There was no significant adverse reaction in both groups. ConclusionYiqi Huoxue decoction can improve cardiac function and the long-term life quality of convalescent in coronary heart disease patients after PCI.