ObjectiveTo evaluate the clinical efficacy of bronchoscopic sputum aspiration combined with bronchoalveolar lavage for treating patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). MethodsA total of 100 patients diagnosed with AECOPD were randomly divided into treatment group (50 cases) and control group (50 cases). The two groups received the same routine therapeutic regimens; meanwhile, the treatment group underwent combined treatment of bronchoscopic sputum aspiration and bronchoalveolar lavage. Clinical efficacy, hospitalization time, and changes in arterial blood gas analysis indicators were compared between the two groups after treatment. ResultsThe total clinically effective rates of the treatment group and the control group were 88.00% and 72.00%, respectively (P＜0.05); the hospitalization time of the treatment group was shorter than that of the control group (P＜0.05). After treatment, PaO2, PaCO2 and SaO2 were improved in both groups in comparison with those before treatment (P＜0.05), and the treatment group got more significant improvements in arterial blood gas analysis indicators than the control group (P＜0.05). ConclusionBronchoscopic sputum aspiration combined with bronchoalveolar lavage can effectively improve the condition of patients with AECOPD and shorten their hospitalization time.

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