目的探讨内镜黏膜下剥离术(ESD)治疗胃底黏膜下肿物的疗效及应用价值。方法回顾性分析经ESD治疗的29例胃底黏膜下肿物患者的临床资料,评估其疗效。结果接受ESD治疗的29例患者中,术中出血较多者2例,最大出血量约20 mL,术中发生穿孔4例。29例胃底黏膜下病变均完全切除,无术后迟发性出血、穿孔等并发症发生。手术时间(70.1±29.3)min,术后住院时间(5.3±1.2)d。术后病理诊断25例为胃肠道间质瘤、4例平滑肌瘤。所有患者经随访4周,无特殊并发症,3个月后复查胃镜创面愈合良好,无复发。结论ESD治疗胃底黏膜下肿物安全、有效,术后并发症发生率低且恢复好。
ObjectiveTo investigate the efficacy and application value of endoscopic submucosal dissection(ESD) for treating gastric fundus submucosal tumors. MethodsThe clinical data of 29 patients with gastric fundus submucosal tumors treated by ESD were retrospectively analyzed, and the efficacy was evaluated. ResultsOf the 29 patients undergoing ESD, 2 cases had intraoperative slightly heavy bleeding, with the maximum bleeding volume of about 20mL, 4 cases suffered from intraoperative perforation. Twenty-nine cases of gastric fundus submucosal lesions were completely dissected, and no postoperative complications occurred, such as delayed bleeding and perforation. Operation duration and postoperative hospital stay were 70.1±29.3 minutes and 5.3±1.2 days, respectively. Twenty-five cases were diagnosed as gastrointestinal stromal tumor and 4 as leiomyoma confirmed by postoperative pathological findings. All patients were followed up for 4 weeks, no special complications occurred, and 3 months later, a rechecking based on gastroscopy exhibited favorable wound healing and no relapse cases. ConclusionESD is a safe and effective therapy for gastric funds submucosal tumors, with a low incidence rate of postoperative complications and perfect recovery.