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临床研究 | 更新时间:2019-03-14
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地佐辛复合丙泊酚在内镜下肠息肉切除术中的应用研究
Study on application of dezocine combined with propofol to endoscopic intestinal polypectomy

微创医学 20191401期 页码:35-37

作者机构:广西南宁市第二人民医院麻醉科,南宁市530031

基金信息:

DOI:10.11864/j.issn.1673.2019.01.10

  • 中文简介
  • 英文简介
  • 参考文献
目的观察地佐辛复合丙泊酚在内镜下肠息肉切除术中的临床效果。方法将行内镜下肠息肉切除术的80例门诊患者随机分为地佐辛组和芬太尼组各40例,麻醉诱导时分别静脉注射地佐辛和芬太尼。对比观察两组患者不同时间点MAP、HR及SpO2、丙泊酚用量、手术时间、苏醒时间、恢复室停留时间、不良反应发生率。结果地佐辛组患者麻醉诱导意识消失时SpO2较高,恢复室停留时间较长,不良反应发生率明显低于芬太尼组(均P<0.05)。结论地佐辛联合丙泊酚相对于芬太尼联合丙泊酚的镇痛效果满意、副作用小,可以安全有效地应用于内镜下肠息肉切除术患者。
ObjectiveTo observe the clinical effect of dezocine combined with propofol on endoscopic intestinal polypectomy. MethodsA total of 80 outpatients undergoing endoscopic intestinal polypectomy were randomly divided into dezocine group and fentanyl group, with 40 cases in each group. The dezocine group and fentanyl group were intravenously administered dezocine and fentanyl during anesthesia induction respectively. The MAP, HR, SpO2, dosage of propofol, operation duration, recovery duration, duration of recovery room stay and incident rate of adverse reactions were compared between the two groups at different time points. ResultsSpO2 in a state of anesthesia-induced unconsciousness was higher, duration of recovery room stay was longer, and the incident rate of adverse reactions was significantly lower in the dezocine group compared to the fentanyl group(all P<0.05). ConclusionCompare with fentanyl combined with propofol, dezocine combined with propofol can obtain a satisfactory analgesic effect with less side effects, and can be safely and effectively applied to the patients undergoing endoscopic intestinal polypectomy.

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