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ERCP 取石后胆总管结石复发的危险因素分析
Analysis of risk factors for recurrence of choledocholithiasis after stone removal by ERCP

微创医学 20191401期 页码:4-8+18

作者机构:广西壮族自治区人民医院消化内科,南宁市530021

基金信息:*通信作者

DOI:10.11864/j.issn.1673.2019.01.02

  • 中文简介
  • 英文简介
  • 参考文献
目的探讨内镜下逆行胰胆管造影术(ERCP)取石后胆总管结石复发的相关危险因素。方法回顾性分析286例诊断为胆总管结石,并接受ERCP取石治疗患者的临床资料,其中取石后胆总管结石复发的42例患者为观察组,未复发的244例患者为对照组,对两组患者的基本资料进行单因素及多因素Logistic回归分析,分析胆总管结石复发的相关危险因素。结果单因素分析显示,两组患者年龄、十二指肠乳头旁憩室发生率、胆总管直径、胆石直径、内镜取石术后胆囊切除率比较,差异均有统计学意义(均P<0.05)。Logistic回归分析显示,胆石直径为经ERCP取石后胆总管结石复发的独立危险因素(OR=1.107,95%CI:1.037~1.182,P=0.002)。结论多种因素与ERCP取石后胆总管结石复发存在关联,术前须对相关危险因素加以评估,尽可能降低胆总管结石的术后复发率。
ObjectiveTo investigate the risk factors for recurrence of choledocholithiasis after stone removal by endoscopic retrograde cholangiopancreatography (ERCP). MethodsClinical data of 286 patients diagnosed as choledocholithiasis and receiving stone removal by ERCP were retrospectively analyzed, among which, 42 patients with recurrence of choledocholithiasis after stone removal were enrolled as observation group and 244 patients without recurrence as control group. Univariate and multivariate Logistic regression analysis were performed on the basic data of the patients in both groups to analyze the related risk factors for recurrence of choledocholithiasis. ResultsThe univariate analysis showed that there were significant differences in the age, incidence of juxtapapillary duodenal diverticulum, choledochal diameter, cholelithic diameter, cholecystectomy rate after endoscopic stone removal between the two groups (all P<0.05). Logistic regression analysis showed that the choledochal diameter was the independent risk factor for recurrence of choledocholithiasis after stone removal by ERCP (OR=1.107, 95%CI: 1.037-1.182, P=0.002). ConclusionMultiple factors are related to the recurrence of choledocholithiasis after stone removal by ERCP, therefore the related risk factors should be assessed before operation to reduce the postoperative recurrence rate of choledocholithiasis.

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