ObjectiveTo analyze the risk factors for re-bleeding after treating upper gastrointestinal bleeding by endoscopic ligation. MethodsForty-six upper gastrointestinal bleeding patients treated with endoscopic ligation were enrolled as objects. The patients were divided into two groups according to the occurrence of re-bleeding after endoscopic ligation, including 20 patients with re-bleeding (observation group) and 26 patients without re-bleeding (control group). The age, gender, blood loss, blood urea nitrogen content, platelet and hemoglobin, shock at admission, endoscopic active bleeding and jet-like bleeding of the lesions were statistically analyzed in the patients of both groups. The univariate analysis was performed, then the indices with statistical difference were enrolled in multivariate analysis. ResultsThere were statistical differences in the blood loss, blood urea nitrogen content, hemoglobin, platelet level, incident rate of shock at admission, rate of malignant tumor bleeding, active bleeding and jet-like bleeding of the lesion between the patients of both groups (P＜0.05). The indices above with statistical difference in the univariate analysis were enrolled in multivariate logistic regression model. The result showed that blood loss, hemoglobin level, malignant tumor bleeding, active bleeding and jet-like bleeding of the lesion were the independent risk factors for re-bleeding in the patients with upper gastrointestinal bleeding(P＜0.05). ConclusionThe risk factors for re-bleeding after treating upper gastrointestinal bleeding by endoscopic ligation includes blood loss, hemoglobin level, malignant tumor bleeding, endoscopic active bleeding and jet-like bleeding of the lesion. Enhanced protective provision for those factor should be performed.

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