ObjectiveTo observe the clinical efficacy of Nano carrier-free drug-coated stent in the treatment of elderly patients with left main coronary artery disease. MethodsTwenty-five elderly patients with left main coronary artery disease were enrolled as objects. All patients were inserted with Nano carrier-free drug-coated stent, and were treated with single-stent or double-stent according to the actual condition of the patient′s vessels. The clinical efficacy of patients was observed at different time points after operation. At 12 months after surgery, coronary angiography was performed in the patients to record the incidence of cardiovascular events, revascularization, restenosis, and acute/subacute thrombosis. ResultsIn the 25 patients, 35 non-carrier drug-coated stents were inserted successfully .The length and diameter of the stents were (20.1±7.6) mm and (3.5±0.5) mm respectively. Single-stent was inserted in 15 cases (60.0%); double-stent was inserted in 10 cases (40.0%) , including 2 cases with Crush Stenting technique, 3 cases with T-stenting technique, 3 cases with Culotte Stenting technique and 2 cases with Simultaneous Kissing Stenting technique. The clinical syndromes disappeared after treatment with Nano carrier-free drug-coated stent in all patients, no death occurred during hospitalization and follow-up, no acute/subacute thrombosis and acute myocardial infarction occurred. ConclusionNano carrier-free drug-coated stent can significantly improve the prognosis and efficacy of elderly patients with left main coronary artery disease.

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