微创医学

目的观察内镜黏膜下剥离术治疗早期胃癌的临床疗效。方法选取108例早期胃癌患者为观察对象，其中接受内镜黏膜下切除术的54例为对照组，接受内镜黏膜下剥离术的54例为观察组。比较两组组织学疗效及手术情况等。结果观察组完整切除率、治愈性切除率均高于对照组（P＜0.05），且手术时间长于对照组，术中出血量、住院时间少于对照组，病灶切除面积大于对照组，VAS评分低于对照组，术后并发症发生率低于对照组（均P＜0.05）。术后随访1年，观察组复发率为9.26%（5/54），明显低于对照组的31.48%（17/54）（P＜0.05）。结论应用内镜黏膜下剥离术治疗早期胃癌，能提高病灶完整切除率及治愈性切除率，较彻底地清除病灶，减少术中出血量，减少术后并发症发生，降低复发风险，安全有效。

ObjectiveTo observe the clinical efficacy of endoscopic submucosal dissection for treating early gastric cancer. MethodsA total of 108 patients with early gastric cancer were enrolled as objects, including 54 patients received endoscopic submucosal resection (control group) and 54 patients received endoscopic submucosal dissection (observation group). The histological efficacy and operative condition were compared between the two groups. ResultsThe complete resection rate and curative resection rate in the observation group were higher than those in the control group（P＜0.05）. Compared to the control group, the duration of operation was longer, the intraoperative blood loss and hospital stay were less, the size of excisional lesion was larger, the VAS scores were lower, The incident rate of postoperative complications was significantly lower in the observation group(all P＜0.05). During the 1-year follow-up, the recrudescence rate of the observation group was significantly lower than that of the control group ［9.26%(5/54) vs.31.48%(17/54), P＜0.05］. ConclusionFor treating early gastric cancer, endoscopic submucosal dissection can increase the complete resection rate and curative resection rate, removes the lesion more completely, decreases the intraoperative blood loss, decreases the incidence of postoperative complications, reduces the risk of postoperative recrudescence, and is safe and effective.