ObjectiveTo analyze the risk factors for residual lesions after cervical conization, thereby to reduce the incidence of residual lesions. MethodsA total of 100 patients with cervical intraepithelial neoplasia and micro-invasive carcinoma were enrolled as objects. The 1-year follow-up was performed after operation, the incidence of residual lesions was recorded, and the related risk factors leading to residual lesions were analyzed. ResultsAll of the 100 patients received cervical conization. Residual lesions occurred in 30 cases after operation, the incident rate of residual lesions was 30.00%. The univariate analysis revealed that the incident rate of residual lesions increased in the patients with more than one type of high-risk human papilloma virus, positive state of incision margin, the lesion range ＞2 quadrants, lesion grade of micro-invasive carcinoma, and the lesion involving the glands (P＜0.05);no significant correlation of age, postmenopausal status, parity history and conization pattern with postoperative residual lesions were found（P＞0.05）.The multivariate analysis results showed that the type of high-risk human papillomavirus, incision margin status, lesion range, lesion grade and involvement of lesion site were the independent risk factors for postoperative residual lesions. ConclusionThe incident rate of residual lesions after cervical conization is high. The lesion involving the glands, more than one type of high-risk human papilloma virus, the lesion range ＞2 quadrants, lesion grade of micro-invasive carcinoma, and positive state of incision margin are the independent risk factors for residual lesions.

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