目的探讨老年冠心病患者经皮冠状动脉介入(PCI)术后支架内再狭窄(ISR)的危险因素。方法回顾性分析382例接受PCI治疗的老年冠心病患者的临床资料,对其ISR的发生情况进行统计,与未发生ISR的患者进行对比分析,探讨ISR的危险因素。结果382例患者行PCI术,共植入支架555支,其中40例患者出现ISR。单因素分析显示,两组合并糖尿病、hsCRP>12 mg/L、支架数量、支架直径、支架长度比较,差异均有统计学意义(P<0.05)。多因素分析发现,合并糖尿病、hsCRP浓度、支架直径、支架长度、支架数量为ISR发生的独立危险因素。结论ISR在老年冠心病患者PCI术后的发生率仍处于较高水平,其中支架直径、长度、数量是ISR发生的独立危险因素;合并糖尿病、hsCRP水平高也会影响ISR的发生,应引起临床重视,给予相应干预,以降低ISR发生率。
ObjectiveTo explore the risk factors of in-stent restenosis (ISR) after percutaneous coronary intervention (PCI) in elderly patients with coronary heart disease. MethodsClinical data of 382 elderly patients with coronary heart disease treated with PCI were analyzed retrospectively. The incidence of ISR was statistically analyzed. The risk factors for ISR were investigated by comparison with the patients without ISR. ResultsA total of 382 patients underwent PC and 555 stents were implanted. ISR occurred in 40 patients. The univariate analysis showed that there were significant differences in cases complicated with diabetes, the proportion of cases with hsCRP >12 mg/L, the number of stents, the stent diameter and the stent length between the two groups (P<0.05). Multivariate analysis revealed that being complicated with diabetes, hsCRP concentration, stent diameter, stent length and stent number were the independent risk factors for ISR. ConclusionThe incidence of ISR after PCI is still at a high level in the elderly patients with coronary heart disease. The stent diameter, stent length and number of stent are the risk factors for the occurrence of ISR. Being complicated with diabetes, high hsCRP level also can affect the occurrence of ISR, thus attention should be paid clinically and the corresponding intervention should be performed to reduce the incidence of ISR.