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腹腔镜术后道地通管汤结肠透析治疗输卵管阻塞性不孕症的临床研究▲
Administration of Daodi Tongguan decoction combined with colonic dialysis after laparoscopy for tubal obstructive infertility

微创医学 201813卷01期 页码:20-22

作者机构:1 广西中医药大学附属瑞康医院,南宁市530001;2 广西合浦县中医院,合浦县530061;3 广西中医药大学,南宁市530001

基金信息:▲基金项目:国家自然科学基金(编号:81360594);广西高校科学技术研究项(编号:YB2014195);广西中医药民族医药传承创新专项(编号:GZLC14-18)
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DOI:DOI:10.11864/j.issn.1673.2018.01.06

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目的观察腹腔镜术后运用道地通管汤结肠透析治疗输卵管阻塞性不孕症的疗效。方法将210例输卵管阻塞性不孕患者随机分为三组,每组70例。A组给予腹腔镜+结肠透析+道地通管汤保留灌肠;B组给予腹腔镜+道地通管汤保留灌肠;C组仅进行单纯腹腔镜下输卵管修复整形术。比较三组的受孕率、输卵管通畅率、疗效及不良反应。结果术后两年内,A组宫内妊娠率为60.00%(42/70),明显高于B组的38.57%(27/70)和C组的27.14%(19/70),差异有统计学意义(P<0.05);但B组和C组比较,差异无统计学意义(P>0.05)。治疗一年半后,三组患者总有效率分别为92.86%、82.86%和55.71%,其中A组与C组、B组与C组比较,差异有统计学意义(P<0.05);A组与B组相比,差异无统计学意义(P>0.05)。半年后,A组未妊娠患者输卵管通畅率为67.11%(51/76),B组为43.56%(44/101),C组为32.14%(36/112),两两比较,差异均有统计学意义(P<0.05)。结论腹腔镜术后运用道地通管汤联合结肠透析可起协同作用,且近期疗效稳定,是治疗输卵管阻塞性不孕症的一种安全有效的方法,值得临床推广应用。
ObjectiveTo observe the efficacy of administration of Daodi Tongguan decoction combined with colonic dialysis after laparoscopy for tubal obstructive infertility. MethodsA total of 210 patients with tubal obstructive infertility were randomly divided into 3 groups, with 70 cases in each group. Group A underwent laparoscopy,colonic dialysis and retention enema with Daodi Tongguan decoction. Group B underwent laparoscopy and retention enema with Daodi Tongguan decoction. Group C only underwent laparoscopic repair and plastic surgery of oviducts.The pregnancy rate, tubal patency rate, efficacy and adverse reaction were compared among the three groups. ResultsWithin 2 years after operation, the intrauterine pregnancy rate of group A [60.00%(42/70)] was higher than that of group B[38.57%(27/70)] or group C [27.14%(19/70)](P<0.05), but there was no significant difference in the rate between group B and group C (P>0.05). After 18 months of operation, the total effective rate of group A(92.86%) or group B (82.86%) was higher than that of group C (55.71%), but there was no significant difference between group A and group B (P>0.05). After six months of operation, tubal patency rate of the patients without pregnancy decreased in the order of group A, group B and group C [67.11% (51/76), 43.56% (44/101) and 32.14% (36/112) respectively, P<0.05)]. ConclusionAdministration of Daodi Tongguan decoction combined with colonic dialysis after laparoscopy can achieve a synergistic effect and stable short-term efficacy, is a safe and effective therapy for tubal obstructive infertility, and is worthy of clinical promotion and application.

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