ObjectiveTo analyze of 24-hour urine component in community patients with complex renal calculi,thereby to better prevent, treat calculi and reduce the recurrent of calculi. MethodsA total of 112 complex renal calculi patients without chronic renal insufficiency (＞18 years of age, urine volume＞400 mL)were enrolled. Then 24-hour urine component was analyzed, and 24-hour urine volume was recorded. Automatic biochemical analyzer was used to detect the levels of urinary calcium, uric acid, magnesium, phosphorus, sodium, potassium and creatinine. Ion chromatography was used to detect the levels of urine oxalate and citrate. ResultsOf 107 patients with calculi, metabolic disturbance was found in 112 cases (95.6%) including 48 cases (44.9%) with reduced urine volume, 21 cases(19.6%) with hypercalciuria, 61 cases (57.0%) with hypomagnesiuria, 38 cases(35.5%) with hypernatriuria, 42 cases (39.3%) with hyperphophauria, 25 cases (23.4%) with hyperuricosuria. Detection of urine oxalate and citrate was not conducted in 9 cases of oxluria due to the equipment condition. Hyperoxaluria and hypocitraturia were found in 36 cases (33.6%) and 82 cases (76.6%) respectively. Among the 107 cases with calculi, there werehad single metabolic disturbance, 2 type of metabolic disturbance, 3 types of metabolic disturbance and 4 types of metabolic disturbance were 11（10.2%）cases ,35（32.7%）cases, 44（43.1%）cases and 14（13.1%）cases respectively. ConclusionMetabolic disturbance exists in most of the residents with complex renal calculi in each community of Guangzhou City. For the the residents with complex renal calculi or the risk factors for recurrence of calculi, 24-hour urine component analysis and comprehensive metabolic assessment should be performed to prevent and treat stones effectively.

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