ObjectiveTo compare the effect on gastrointestinal motility after gastric perforation between laparoscopic and open repair. MethodsEighty-four patients with acute gastric perforation were divided into observation group and control group according to the principle of random and double-blind, with 42 cases in each group. Routine open repair and minimally invasive laparoscopy were conducted in the control group and observation group respectively. The serum gastrin levels at postoperative 1h, 24h and 48 h, the durations for postoperative exhausting and bowel sound recovery, hospital stay, incidence of operative complications and postoperative recrudescence were compared between the two groups. ResultsThe serum gastrin levels at postoperative 1h, 24h and 48h were higher in the observation group compared to the control group （all P＜0.05）. In the observation group, the durations for postoperative exhausting and bowel sound recovery, early ambulation and postoperative hospital stay were shorter compared to the control group（all P＜0.05）. The incident rate of postoperative complications in the control group was higher than that in the observation group (19.0% vs. 4.8%,P＜0.05). The recrudescent rate of observation group was lower than that of the control group (2.38% vs. 14.29%, P＜0.05). ConclusionCompared to the open repair, laparoscopic surgery has the advantages of faster recovery of gastrointestinal motility, shorter hospital stay and promotion of rehabilitation.

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