ObjectiveTo observe the clinical efficacy of electroacupuncture and acupoint blood-letting therapy combined with carbamazepine and mecobalamin in the treatment of postherpetic neuralgia. MethodsSixty patients with postherpetic neuralgia were randomly divided into experimental group and control group, with 35 cases in each group. The control group was orally administered carbamazepine and mecobalamin, and the experimental group was treated with electroacupuncture and acupoint blood-letting therapy on this basis. The Visual Analogue Scale（VAS）score , serum P substance level and efficacy were observed and compared between the two groups. ResultsAfter treatment, the VAS scores and serum P substance levels significantly decreased in both groups, and those indices above were significantly lower in the experimental group compared to the control group (all P＜0.05). The total effective rate of the experimental group was higher than that of the control group, but no significant difference was found (P＞0.05). ConclusionElectroacupuncture combined with acupoint blood-letting therapy on the basis of carbamazepine and mecobalamin is an effective therapeutic approach for postherpetic neuralgia, and can relieve the pain of patients and improve the quality of life.

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