ObjectiveTo investigate the value of endoscopic retrograde cholangiopancreatography (ERCP) applied to elderly patient with stenosis of bile duct. MethodsClinical data of 101 elderly patients ( age＞60 years ) undergoing ERCP due to stenosis of bile duct were retrospectively analyzed. And the etiology, treatment and postoperative complications were statistically analyzed. ResultsThe 101 elderly patients with stenosis of bile duct consisted of 31 cases with benign stenosis (30.69%) and 70 cases with malignant stenosis (69.31%). Inflammatory stenosis was the main cause of benign stenosis of bile duct,accounted for 67.74%(21/31). Cholangiocarcinoma was the most common cause of the malignant stenosis of bile duct, accounted for 71.43%（50/70）. The lower segment of common bile duct was the common section for stenosis accounted for 50.50%(51/101). Among the 101 patients, nasal bile duct drainage was conducted in 29 patients and biliary drainage in 72 patients (including 65 cases placed with plastic stents and 7 cases placed with metal stents).After ERCP, the symptoms of biliary obstruction were improved in all cases. The total bilirubin and direct bilirubin levels significantly decreased at 1 week and 2 weeks after operation compared to the preoperative levels (all P＜0.05).Complications occurred in 8 cases including 2 cases with mild pancreatitis, 5 cases with hyperamylasemia and 1 case with cholangitis, and the conditions of all these patients were improved after treatment. ConclusionsERCP can effectively alleviate the obstruction caused by benign or malignant stenosis of bile duct, and can improve the liver function of patients. This approach is the first interventional therapy for stenosis of bile duct.

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