【Abstract】 ObjectiveTo investigate the feasibility and efficacy of endoscopic appendical cavity irrigation in the treatment of acute simple appendicitis. MethodsSixty patients with acute simple appendicitis who met the inclusion criteria were randomly divided into the patients treated with endoscopic therapy group (n=30, observation group) or with traditional laparoscopic surgery(n=30, control group).The durations of abdominal pain improvement and postoperative feeding, the ambulation time, postoperative complications, hospital stay and hospitalization expense were assessed and compared between the two groups. ResultsThe durations of abdominal pain improvement and postoperative feeding, ambulation time and hospitalization expense in the observation group were （1.06±0.10）d, （3.86±0.38）h,（3.00±0.55）h and （5 341.3±706.3）yuan. The durations of abdominal pain improvement and postoperative feeding, ambulation time and hospitalization expense in the control group were （1.54±0.04）d, （24.00±0.01）h,（14.12±1.29）h and （9 148.10±403.10））yuan. And there were significant differences in the indexes above between the two groups（P＜0.01）. The hospital stay of the observation group and control group were (6.64±0.70) d and（7.12±0.36）d respectively. No postoperative complications including bleeding, perforation and infection occurred in both groups. During the followup of 1 years , the recurrence rate of the observation group was 3.33% (1/30), but no recurrence was observed in the control group.ConclusionEndoscopic appendical cavity irrigation for acute simple appendicitis is safe and effective, and has the advantages of simple operation, less trauma, less bleeding loss and being scarless, can rapidly improve the symptoms and the quality of life of patients, and can reduce the hospitalization costs.

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