目的分析不同年龄组同期施行心脏瓣膜手术和冠状动脉旁路移植术(CABG)的效果及临床经验。方法同期接受心脏瓣膜手术和CABG的患者80例,根据年龄分为≥60岁组(n=44)和<60岁组(n=36),均在全麻体外循环(CBP)下完成手术,其中二尖瓣置换(MVR)42例,主动脉瓣置换(AVR)23例,双瓣膜置换(DVR)15例。术中搭桥平均(1.5±0.6)支,其中1支桥38例,2支桥27例,多支桥15例。共移植旁路血管127支。结果两组患者术后呼吸机辅助通气时间、CSICU监护时间、住院时间、围术期并发症、死亡率比较,差异均无统计学意义(P>0.05)。随访79例,失访5例,1例3个月后死于严重低心排综合征(LCOS),1例1年后因瓣周漏(PVL)行2次换瓣,2例出现脑血管意外。其余患者生活质量改善明显,心功能Ⅰ级56例、Ⅱ级14例。结论心脏瓣膜手术联合CABG是治疗心脏瓣膜病变合并冠心病的有效方法,可使患者获得满意的治疗效果。
ObjectiveTo analyze the results and experiences of cardiac valve surgery combined with coronary artery bypass grafting (CABG) in different age groups. MethodsThe clinical data of 80 patients,who received cardiac valve surgery combined with CABG,were divided into ≥60 years group(44 cases) and <60 years group( 36 cases), according to their ages. All the operations were performed under general anesthesia and cardiopulmonary bypass (CPB), including mitral valve replacement (MVR) in 42 cases, aortic valve replacement (AVR) in 23 cases and dual valve replacement (DVR) in 15 cases. The mean grafts number was (1.5±0.6) branches. Among the CABG, 38, 27 and 15 cases were transplanted with 1, 2, and multiple grafts respectively. A total of 127 bypass grafts were grafted. ResultsThere were no significant differences in the duration of postoperative ventilator-assisted ventilation, CSICU monitoring time, hospitalization time, perioperative complications and mortality between the two groups (P>0.05). 79 patients were followed up, 5 patients lost, 1 patient died of severe Low Cardiac Output Syndrome (LCOS) after 3 months, 1 patient suffered from para-valvular leakage (PVL) operated the second valve replacement in 1 year later, 2 patients had cerebro-vascular accident. The remaining patients improved the quality of life significantly, 56 patients were in NYHA class Ⅰ, 14 patients were in NYHA class II. ConclusionCardiac valve surgery combined with CABG is an effective method in the treatment of heart valvular disease with coronary heart disease, which can make the elderly patients obtain satisfactory therapeutic effect.