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两种麻醉方法用于小型猪肺动脉高压模型建立的对比研究▲
Comparative study of two kinds of anesthesia methods to establish the model of miniature pigs pulmonary arterial hypertension

微创医学 201401期 页码:52-54

作者机构:(1 广西中医药大学第一附属医院麻醉科,南宁市530023;2 广西医科大学第一附属医院心血管病研究所手术麻醉科,南宁市530021)

基金信息:▲基金项目:广西中医药大学第一附属医院青年科学基金项目(编号:GZYQJ2012012)*通讯作者

DOI:10.11864/j.issn.1673.2014.01.17

  • 中文简介
  • 英文简介
  • 参考文献
目的对比两种麻醉方法用于小型猪肺动脉高压模型建立的效果。方法选择24头广西巴马香猪,随机分为A组(静脉复合腹腔注射组)(n=12)与B组(静吸复合麻醉组)(n=12),比较两种麻醉方法的麻醉效果及死亡率。结果A组优9例、良3例、差0例、麻醉死亡0例,死亡率为0;B组优8例、良2例、差0例、麻醉死亡2例,死亡率为16.7%。两组组间麻醉效果比较差异无统计学意义(Z=-0.652,P=0.515),死亡率B组高于A组。结论在一些短小的小型猪外科手术中,静脉复合腹腔注射可使麻醉过程更平稳,是一种安全、有效、可行的麻醉方法。
ObjectiveTo observe the effect of two kinds of anesthesia methods used to establish the model of miniature pigs’ pulmonary arterial hypertension. MethodsTwentyfour Guangxi Bama miniature pigs were rand omly divided into group A (combined intravenous and intraperitoneal injection group) or group B (intravenous inhalation combined anesthesia group), each had 9 pigs. Anesthetic effect and mortality of the two groups were compared. ResultsThe anesthetic effect was excellent in 9 pigs, good in 3 pigs, poor in 0 pig, death in 0 pig, in group A, as compared to excellent in 8 pigs, good in 2 pigs, poor in 0 pig, death in 2 pigs. The mortality rate of group B was higher than that of group A (16.7% versus 0%). There was no statistical significance in the other anesthetic effect between the two groups. ConclusionCombined intravenous and intraperitoneal injection for surgical operations in some short miniature pigs can make the anesthesia process more stable, indicati ng it as a safe, effective, and feasible anesthesia method
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