ObjectiveTo compare the efficacy and safety of craniotomy surgery and minimally invasive surgery in the treatment of cerebral hemorrhage. Methods77 patients with hypertensive cerebral hemorrhage were randomly divided into craniotomy group (39 cases) and minimally invasive group (38 cases) by random digits table. Craniotomy group were treated with conventional craniotomy surgery; minimally invasive group were with minimally invasive hematoma evacuation and drainage. The operation time, amount of bleeding, hematoma clearance rate, hospital stay, postoperative 3 months mortality rate, short-term (3 months) and long-term(12 months) excellence rate of the two groups were observed. ResultsThe operation time and hospital stay of minimally invasive group were significantly shorter than those of craniotomy group, the difference was statistically significant (P＜0.05); the blood loss in minimally invasive group was (54.01±4.63）mL,less than (210.02±5.52mL) in the craniotomy group, the difference was statistically significant (P＜0.05). There was no significant difference in the rate of hematoma clearance between the two groups (P＞0.05). After 3 months of operation, the mortality of craniotomy group was 30.77% (12/39), the mortality of minimally invasive group was 5.26% (2/38), the difference was statistically significant (P＜0.05). The short-term and long-term excellence rate of the two groups was not statistically significant (P＜0.05). ConclusionThe treatment of non-progressive hypertensive cerebral hemorrhage, the clinical efficacy of minimally invasive surgery was significantly better than that of traditional craniotomy.

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