ObjectiveTo research the correlation of injured vertebral angiography dispersity and VDR gene polymorphisms in osteoporotic thoracolumbar fracture. MethodA total of 60 cases with osteoporotic thoracolumbar fracture, treatment with percutaneous vertebroplasty. Preoperative, detect system for VDR genotypes of peripheral blood in patients. Intraoperative, watch bone contrast agents were dispersed in patients and watch bone cement dispersion in vertebral body and leakage, and so on,then studied the correlation of injured vertebral angiography dispersity and VDR gene polymorphisms. ResultsSystem detected in 60 patients with VDR genotype BB 0 cases, Bb 28 cases, bb 32 cases. Injured vertebral angiography dispersion was in good condition.In 60 cases of 110 injured vertebrals，85 vertebrals were all the dispersion, VDR genotype Bb 52cases, bb 33 cases.The degree of contrast between different genotypes in patients with diffuse comparative difference was statistically significant (P＜0.01).There are 9 vertebral bodys bone cement leakage happened.However, no spinal canal leakage, and no obvious complication happens. In which the VDR genotype Bb 7 cases, bb 2 cases. Between the different genotypes in patients with bone cement leakage was no statistical significance (P＞0.05). ConclusionThere are certain correlation in injured vertebral angiography dispersity and VDR gene polymorphisms in Osteoporotic thoracolumbar fracture. In Bb genotype,the contrast agents are more fully , and the ratio of bone cement leakage is higher also.

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