ObjectiveTo observe the biological characteristics of orbital adipose cells in Graves’ ophthalmopathy patients. MethodsTwelve Graves’ ophthalmopathy patients undergoing orbital decompression surgery were selected as the object of observation, orbital adipose tissues specimens were obtained in the course of surgery.Those adipose tissues were cultured in vitro by enzymatic digestion culture method，maked Sudan III staining and pathological examination.Observed the morphological features of adipose cells from active phase and inactive phase patients. ResultsDuring the in vitro cultivation of adipose tissues,The orbit branch polygon cells were induced into mature adipose cells. The number of branch polygon cells in active patients were significantly more than inactive patients, the difference was statistically significant between the two groups（P＜0.05）. There was a large number of lymphocytes infiltrated in the orbital adipose tissue of active patients，this kind of situation did not appear on inactive patients. ConclusionThe adipose tissue hyperplasia in active period were more active than those in inactive period.

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