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0.3% 玻璃酸钠滴眼液对微创白内障超声乳化术后泪膜的影响▲
Influences of 0.3% Sodium Hyaluronate Eye Drops on the tear film’s function of patients after phacoemulsification

微创医学 201605期 页码:669-672

作者机构:广东省深圳市宝安区人民医院眼科,深圳市518101

基金信息:▲基金项目:广东省深圳市宝安区科技计划社会公益项目(编号:2015031);作者简介:牛静宜(1983~),女,博士,主治医师,研究方向:白内障。

DOI:DOI:10.11864/j.issn.1673.2016.05.03

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目的探讨0.3%玻璃酸钠滴眼液对微创白内障超声乳化吸出联合人工晶体植入术后泪膜的影响。方法将单纯性老年性白内障患者52例(60只眼),随机分为A组27例(31只眼)和B组25例(29只眼)。两组均行白内障超声乳化吸出联合人工晶体植入。A组术后除常规用药外还给予0.3%玻璃酸钠滴眼液治疗;B组术后仅给予常规用药。记录患者术前及术后1天、1周、2周、1个月的角膜荧光素染色(FL)、泪液分泌试验(SⅠt)、泪膜破裂时间(BUT)等,同时进行干眼主观症状评分。结果术后1d、1周、2周,A 组干眼症状评分均低于B 组,两组比较,差异有统计学意义(P<0.05)。术后1个月,两组干眼症状评分比较,差异无统计学意义(P>0.05)。术后1d、1周、2周、1个月,A组与B组相比,BUT明显延长(P<0.05),FL着色密集度明显减少(P<0.05),SⅠt浸湿滤纸长度明显增加,两组比较,差异均有统计学意义(P<0.05)。结论白内障术后常规应用玻璃酸钠滴眼液很有必要,可有效改善干眼症状,值得临床推广。
ObjectiveTo explore the influence of 0.3% Sodium Hyaluronate Eye Drops on the tear film’s function of patients after phacoemulsification. MethodsA total of 52 patients with age related cataract (60 eyes) were divided into group A(31 eyes) and group B(29 eyes). Both patients were performed phacoemulsification. After phacoemulsification, patients of group A were treated with 0.3% Sodium Hyaluronate Eye Drops and patients of group B (30 eyes) were treated with conventional therapy. Corneal fluorescein staining (FL), schirmer test (SIt), break-up time (BUT) and dry eye symptom scores were recorded before and 1 day, 1 week, 2 weeks, 1 month after operation. ResultsAfter 1 day, 1 week, 2 week of operation, the dry eye symptom scores in group A were lower than those in group B, the difference was statistically significant between the two groups(P<0.05) . At 1 month of operation, there was no significant difference in dry eye symptom scores between the two groups(P>0.05). At 1 day,1 week,2 week,1 month postoperative, BUT was longer,FL was less,SIt was increased in group A with significant statistical differences (P<0.05). ConclusionUsing 0.3% Sodium Hyaluronate Eye Drops after phacoemulsification can improve dry eye symptoms of patients and accelerate the recovery of the tear film.

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