目的比较喉环状软骨上部分切除术与传统部分喉切除术治疗喉鳞癌的临床疗效。方法将70例患者分为观察组和对照组各35例。观察组采取喉环状软骨上部分切除术,对照组采取传统部分喉切除术治疗。随访5年,比较两组手术效果。结果观察组34例患者成功拔管,总拔管率为97.14%(34/35);对照组29例成功拔管,总拔管率为82.86%(29/35),两组比较,差异有统计学意义(P<0.05)。两组患者随访5年原发灶复发、颈部复发及远处转移率比较,差异无统计学意义(P>0.05)。两组患者1年、3年、5年生存率比较,差异无统计学意义(P>0.05)。结论喉环状软骨上部分切除术治疗喉鳞癌,比传统部分喉切除术治疗气管套管拔管率高,未增加原发灶复发、颈部复发及远处转移率,患者远期生存率无明显差异。
ObjectiveTo compare the clinical effect ofsupracricoid partial laryngectomy andtraditional partial laryngectomyin the treatment oflaryngeal squamous cell carcinoma. MethodsA total of 70 patients with laryngeal squamous cell carcinoma were divided into experiment group(35 cases) and control group(35 cases).Patients in experiment group were treated with supracricoid partial laryngectomy, patients in control group were treated with traditional partial laryngectomy. After 5 years of follow-up, the effect of the two groups was compared. ResultsThe decannulation rate of experiment group was 97.14%(34/35), the decannulation rate of control group was 82.86%(29/35), the decannulation rate for the experiment group was higher than the control group, the difference was statistically significant (P<0.05). There were no significant differences on the rate of recurrence of primary tumors, regional recurrence, distant metastasis of the two groups(P>0.05). There were no significant differences on 1, 3, 5 years survival rate(P>0.05). ConclusionIt has good trachea cannula decannulation rate, and never increase the rate of recurrence of primary tumors, regional recurrence, distant metastasis, with no visible difference for long term survival rate.