ObjectiveTo observe the safety and feasibility of propofol TCI in hysteroscopic surgery. MethodsA total of 80 patients with hysteroscopy were randomly divided into control group and observation group. After intravenous injection of 2 g/kg fentanyl, the control group was given intravenous injection of propofol 2 mg/kg to 80-150 μg/kg·min intravenous infusion to maintain constant speed anesthesia; Observation group were administered TCI system with initially 2 μg/mL plasma concentration as the standard, to 4.7 μg/mL when cervical dilation, then rake concentration provided at 3.3μg / mL to the end of surgery. ResultsThe amount of propofol between the two groups was not statistically significant(P＞0.05); The unconsciousness time,recovery time, MAP, HR,SpO2 of the observation group were higher than those of control group,the differences were statistically significant (P＜0.05 ). Conclusionpropofol TCI used to anesthesia intrauterine operation have the advantage of rapid hypnogigia ,rapid recovery and more smooth of vital sign than intravenous infusion.

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