微创医学

目的通过测定左室高电压患者血浆脑尿钠肽（BNP）及心脏彩超测量室间隔（IVS）变化，探讨左室高电压的病因及其预后。方法选取经心电图诊断为左室电压正常者68例为对照组；心电图诊断为左室高电压的患者65例为左室高电压组，根据患者伴发疾病情况将左心室高电压组进一步分为合并高血压组（35例）和正常血压组（30例），分别测定各组患者的BNP和IVS数值。结果对照组BNP和IVS分别为（23.48±7.15）pg/mL和（9.0±0.8）mm，左室高电压组BNP和IVS分别为（65.00±9.80）pg/mL和（11.0±0.6）mm，两组比较，差异有统计学意义（P＜0.05）。合并高血压组BNP和IVS分别为（95.39±22.81）pg/mL和（12.01±0.90）mm，无合并高血压组BNP和IVS分别为（50.11±15.01）pg/mL和（10.23±0.60）mm，两组比较，差异有统计学意义（P＜0.05）。结论左室高电压患者的BNP及IVS较正常者有明显升高，可能影响其预后。

ObjectiveTo investigate the etiology and prognosis of left ventricular voltage through the determination of plasma brain natriuretic peptide in patients with left ventricular high voltage in (BNP) and echocardiography to measure ventricular septal (IVS) changes. MethodsA total of 68 patients with left ventricular normal voltage were selected as control group, and 65 patients with high left ventricular (LV high voltage group) were selected as left ventricular high voltage group. According to the patients associated disease, patients with left ventricular high voltage group were divided into hypertension group (35 cases) and normal blood pressure group (30 cases). BNP level and IVS in each group was detected. ResultsThe BNP level and IVS of control group were (23.48±7.15) pg/mL and (9.0±0.8) mm respectively, and the BNP level and IVS of left ventricular high voltage group were (65.00±9.80)pg/mL and（11.0±0.6）mm, the difference was statistically significant (P＜0.05). The BNP level and IVS of hypertension group were (95.39±22.81)pg/mL and（12.01±0.90）mm, and the BNP level and IVS of normal blood pressure group were（50.11±15.01）pg/mL and（10.23±0.60）mm, the difference was statistically significant (P＜0.05). ConclusionThe level of BNP and IVS of left ventricular high voltage patients were significantly higher than health people, and may have a potential impact on the prognosis of the patients with high left ventricular.