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超声内镜引导下聚桂醇注射治疗胰岛素瘤的初探▲
Preliminary study of endoscopic ultrasound guided polidocanol injection of insulinoma

微创医学 201603期 页码:313-315

作者机构:广西医科大学第一附属医院 1 消化内科;2 内分泌科;3 胃肠腺体外科;4 病理科,南宁市530021

基金信息:▲基金项目:国家自然科学基金(编号:No.31360221);广西自然科学基金(编号:No.2012GXNSFAA053140);广西教育厅基金(编号:桂教科研 LX2014076)
作者简介:覃山羽(1973~),女,博士,教授,研究方向:超声内镜诊治消化道肿瘤。
 *通讯作者

DOI:DOI:10.11864/j.issn.1673.2016.03.01

  • 中文简介
  • 英文简介
  • 参考文献
目的探讨超声内镜(EUS)引导下聚桂醇注射治疗胰岛素瘤的可行性及安全性。方法72岁胰岛素瘤患者1例,经实验室、影像学和超声内镜细针穿刺(EUS-FNA)确诊,患者存在反复低血糖发作症状,给予经超声内镜向瘤体内注射10 mL ∶100 mg聚桂醇0.9 mL进行干预。动态观察低血糖症状、血糖等实验室指标及影像学变化。结果患者术后低血糖发作症状消失,血糖渐升高至正常,实验室及影像学检查证实其获得完全缓解,术后第5天出院。结论聚桂醇可作为新的硬化剂安全地用于超声内镜引导注射治疗胰岛素瘤,值得扩大病例进一步研究。
ObjectiveTo explore the feasibility and efficacy of endoscopic ultrasound (EUS) guided polidocanol injection of insulinoma. MethodA 72-year-old woman with insulinoma, confirmed bylaboratory, imaging examinationandEUS-FNA,had recurrent hypoglycemiaepisodessymptoms,was intervenedby EUS-guided injection into the insulinoma with a total amount of 0.9 mL polidocanol (10 mL ∶100 mg). ResultWith blood glucose went to normal eventually, no further hypoglycemic episodes was observed. Laboratory test and imaging examination indicated completed remission. The patient was discharged 5 days after the procedure. ConclusionMinimally invasive EUS-guided polidocanol ablation may be an novel alternative choice for patients with insulinoma, further study could be carried out to confirm the efficacy and feasibility.

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